Determination of Cylindrospermopsin in Surface and Treated Water using Liquid Chromatography-Tandem Mass Spectrometry

Cylindrospermopsin (CYN) is an emerging freshwater cyanobacterial toxin, and its reports on toxicity toward the human liver kidney tissues has drawn a lot of attention. An appropriate analytical method necessary to determine presence this toxin in water resources including drinking water; therefore, it develop sensitive for CYN detection. In study, we developed simple detection using liquid chromatography-tandem mass spectrometry (LC-MS/MS) direct injection. The was validated linearity calibration, limit detection, quantitation, accuracy, precision. quantitation were range 0.029 μg/L 0.091 μg/L, respectively. Accuracy precision also obtained within acceptable range. optimized used measure concentrations surface from each weir areas Geum River, Nakdong River. Additionally, applied samples treatment plants River process.